Below is a listing of all the National Champions in Mount Holyoke history from both the team and the individual era.
TEAM
IHSA National Championship
| Year | Program |
| 1986 | Riding |
| 2000 | Riding |
| 2006 | Riding |
Individual
NCAA Division III Track & Field
| Year | Student-Athlete | Event |
| 1998 | Amanda Salb | Shot put |
| 1999 | Amanda Salb | Shot put |
Riding
IHSA Individual National Champions
| Year | Student-Athlete |
| 1982 | Anne Sipperly |
| 1982 | Ani Shaker |
| 1986 | Hilary Kissel |
| 1986 | Chris Nickelson |
| 1986 | Annemarie Hurtgen |
| 1986 | Kim Raye |
| 1987 | Jeannie McCoy |
| 1990 | Claudia Barth |
| 1990 | Ingrid Carlson |
| 1991 | Barbara Brady |
| 1992 | Krista Johnson |
| 1992 | Emily Straw |
| 1993 | Carter Iseman |
| 1997 | Lessa Millard |
| 1997 | Chelsea Hofstrod |
| 1997 | Amber Summers |
| 1999 | Ali Feinburg |
| 2002 | Janet Obee |
| 2004 | Melissa Rabbit |
| 2004 | Sara Royston |
| 2005 | Kyla Makhloghi |
| 2006 | Danielle Johnson |
| 2009 | Mignon Johnston |
| 2013 | Abby Raucher |
| 2014 | Felicia Harrsch |
| 2015 | Anne Waldo |
| 2016 | Sabrina Fox |
| 2017 | Sara Hearn |
| 2018 | Sara Hearn |
Cacchione Cup (Nation's Top Individual Riding Honor)
| Year | Student-Athlete |
| 1990 | Claudia Barth (Fitch Cup) |
| 2002 | Laena Romond |
| 2010 | Lindsey Sceats |